Peter Tieleman


Peter Tieleman conducts research in biological membranes, a field that could inform the design of drugs. He has developed a new analysis software for membrane simulations, which he has made available on his website.

This research is focused on understanding the fundamental properties of biological membranes. Biological membranes are primarily made of lipids and proteins that form a very strong wall around every cell, but still allow transport of a broad range of molecules as well as information across this wall. Compute Canada infrastructure is used to simulate the components of cell membranes at a very detailed level, down to every single lipid, protein and water molecule. The results of this research have the potential to impact Canadians by providing a better fundamental understanding of biological processes involving cell membranes, which, in the longer term, enables the rational design of drugs for diseases we cannot currently effectively cure. This research would not be possible without Compute Canada because models of biological systems at the level of individual atoms and molecules require the large-scale computational facilities only Compute Canada offers.